From Los Angeles to San Francisco on Highway One

From Los Angeles to San Francisco on Highway One

You can Travel between San Francisco and Los Angeles on Coastal Highway One
Total Distance: 270 miles (San Luis Obispo to San Francisco)
Driving Time: All day or longer. You'll average no more than 30 to 40 miles per hour.

If have a choice when driving between Los Angeles to San Francisco, start in LA to avoid afternoon traffic jams. Going south, leave San Francisco early to avoid morning rush and have the best chance of getting to LA before backups begin.

If you plan to make the trip in one day, driving this section of Highway 1, it will take 9 to 10 hours. Available daylight varies from 10 hours in December-January to almost 15 hours in June-July.

I find a site, You can give a try: http://www.cashuttlebus.com/index.asp
They have bus from LA to SF,bus from LA to SF.